In a couple of months I'll have 2 years on the E+3 model. Although I only have 1600km (1000 miles) on it, here a little summary again. The low mileage is purely because I mostly ride bio bikes in the summer.
Until now no signs of frame or paint cracking. It has survived some nasty crashes in the rocky mountains of Italy in Finale Ligure with some battle scars, but it stills runs awesome. Tried out high setting once, but kept it at low since then. I started replacing parts that failed early on in the journey. Here a small list:
-Replaced MT420 brakes for some orange Hope Tech4 V4.
-Brake rotors to 220/200 SRAM HS2
-Upgraded the domain fork with a rc2.1 damper unit
-switched the DPS dampfer to an X2 Elite from an E+1 model and shortly after to the Super Deluxe Coil Ultimate RC2T (which is awesome in the bike)
-handlebars to some OneUP carbonbars with ODI grips
-changed dropper to a 240mm OneUP (fits perfectly in the XL frame, old dropper that came with the bike failed and with 170mm the saddle got me bruises on the inside of my thighs on long, steep decents)
-replaced wheels to Mavic E-deemax (nuts for the bearing play on the original wheel front hub kept getting loose every 2nd ride, rear rim broke twice)
I am still running the deore drivetrain, which I really, really like. I broke 2 derailleurs on tight sections, but for a price of around 30€ in germany it does not brake the bank. Cassette holds up nicely, same with the original kmc chain. Had to get a pair of new cranks after a crash where one of them bent by quite a bit.
As for the rest, the motor holds up nice, battery as well. Never had any more issues with the motor after my initial problems when flashing new firmware, where it basically went dead for 2 weeks. The only issue I have since the beginning besides the rather cheap parts on the lowest E+3 model is the clearance below the motor. The cover holds up nicely though for the beating. Only broke one of them, but got 2 spare ones waiting
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think that's new from giant. 
