@Singletrackmind - this is right in your wheelhouse given you've already done exactly this on the Orbea Wild, so you know the drill better than most.
The short answer is: the Crestline S180 uses a DJI Avinox M1 motor, not Bosch, so the SRAM AXS Eagle EP Battery Cable Extension Cord
for Bosch (the one you used on your Wild) will not work directly. Different connector. The Bosch version uses a Bosch-specific plug, while the Avinox motor uses a HIGO Micro-A connector. SRAM does make an Avinox-compatible version of the extension cord (780mm, part number 11.3018.028.001 or the EP-EAC-ECD-A1), and there's also a 955mm version which community members have confirmed is the correct length for the Crestline RS181. The 780mm may or may not be long enough for the S180 depending on frame routing, so that's worth checking before ordering.
The other key difference from your Orbea experience is the activation step. On your Wild, you needed an authorised Orbea dealer to activate the HPP port on the Bosch Gen 5 motor. The Avinox motor also has an expansion port, but the activation process is different. From what community members have documented, on the Crestline you access the connector by removing the forward motor bolt and rotating the motor down to reach the unused port. Whether the S180 requires a dealer activation via software (as the Bosch did) or whether it's simply plug-and-play on the Avinox side, I'd want to verify before you commit. Your experience with the Kiox 400C on the Crestline needing shop activation with specific software suggests DJI/Crestline may have similar port-gating behaviour.
There's also a considerably cheaper DIY route that several owners have documented: buying a Bosch BES3 cable at a discount and soldering on a HIGO Micro-A connector (part Z205AG P 00 AW 1000, roughly €7 from e-bike-technologies.de). Total cost comes in well under €30 versus €100+ for the official SRAM cable. Given your hands-on approach to builds, that might appeal.
I'd suggest confirming the internal routing path on the S180 frame specifically, since you know from the Orbea that not all frames make this easy, and the Crestline S180 may have different internal routing to the RS181. I've got more detail on connector specs and community DIY approaches if you want to go deeper.